RApid hpv
diagnostics

We develop an abbreviated method to diagnose the two most oncogenic types of human papillomavirus

About the project

Genetics for diagnosis

We are developing a diagnostic method for the two most oncogenic types of human papillomavirus (HPV): HPV type 16 and HPV type 18.

We want to replace the previous lengthy diagnostic methods with a shortened and equally effective diagnostic that does not require the full procedure of isolating genetic material from throat swabs and saliva. Thanks to the simplified sample procedure technique, it will be possible to use an approach known as Direct-LAMP – simplifying the tedious process of isolating genetic material.

More about our technology

Our mission

Simplified diagnostics

The human papilloma virus is one of the most common sexually transmitted viruses in the world. According to the World Health Organization, there will be about 604,000 new cases of cervical cancer worldwide in 2020, and about 342,000 deaths from the cancer.

HPV testing can help detect cervical cancer even before the onset of symptoms or changes visible on imaging tests, resulting in effective treatment and reduced risk of death.

Our goal is to make this form of virus diagnosis widely available and affordable.

More about the risks associated with HPV

our technology

Direct-LAMP tests

The Real-Time LAMP (Real-Time Loop Mediated Isothermal Amplification) method is a modern and advanced molecular diagnostic technique that allows rapid and precise detection of genetic material of HPV types 16 and 18, which are considered the most oncogenic types of this virus.

The method is based on the amplification (duplication) of specific fragments of viral DNA in an isothermal reaction, that is, at a constant temperature. As a result, there is no need for thermal cycling, as with other DNA amplification methods such as PCR (Polymerase Chain Reaction). This is one of the main advantages of the Real-Time LAMP method, as it allows faster reaction times and simplifies the diagnostic procedure.

The Real-Time LAMP method is very precise and sensitive, allowing accurate detection of the presence of the virus under test in throat swabs or saliva samples. The results are monitored in real-time, allowing for real-time observation of the DNA amplification process. This diagnostic technique is also resistant to inhibitors found in clinical samples, minimizing the risk of false-negative or false-positive results. The Real-Time LAMP method is also very useful in the initial validation of diagnostic kits, and due to its precision and sensitivity, it can be used to evaluate the performance of newly developed diagnostic kits, as well as to compare results with other diagnostic methods to confirm their accuracy and reliability.